Introduction
If you are a diabetic person, wouldn’t you like to know if you are at risk of developing Cardiovascular Complications?
Savyon Haptoglobin Typing ELISA test is a once in a life time test that can indicate if a particular patient is at high risk for this diabetic complication and may benefit from vitamin E supplementation!
The Haptoglobin (Hp) Typing ELISA is intended for use for diabetic patients only, for the qualitative determination of Hp phenotypes (Hp 1-1, Hp 2-1, or Hp 2-2) in human serum/plasma, to be used in conjunction with clinical evaluation and patient assessment as an aid in predicting risk of coronary arterial and cardiovascular disease.
Hp genotyping has a predictive value in diagnosing cardiovascular disease development in diabetic patients. Diabetes is also a predisposing factor for infections. People with diabetes have a two to four times greater risk of systemic infection than people without diabetes. Variation in Hp genotype is also implicated as a contributing factor to mortality from both extracellular and intracellular pathogens.
Hp genotypes include Hp1-1, Hp1-2, and Hp2-2. The frequency of the HP1 and HP2 genes varies worldwide depending on racial origin: the HP1 frequency varying from about 0.07 in parts of India to over 0.7 in parts of West Africa and South America, and HP2 being most prevalent in India. Both HP1 and HP2 have been linked to susceptibility to various diseases.
Of the three known Hp genotypes, the Hp2-2 genotype is considered to be a major susceptibility gene for people with type 2 #diabetes because it results in reduced antioxidant capacity. Hp2-2 patients have also been found to have higher mortality and poorer outcomes from viral and microbial infections than other genotypes.
Savyon Diagnostics Haptoglobin Typing ELISA test kit offers a simple means for Hp Typing using as little as 15 uL of serum or plasma without the need for electrophoretic analysis. The test was developed by Prof. Andrew Levy from the Technion Institute in Israel who has published numerous articles on the benefits of testing for Hp typing.
More information about Haptoglobin Typing can be found in the publications section.