The QuickStripe™ RSV is a rapid qualitative immunochromatographic assay for the detection of respiratory syncytial virus (RSV) antigens in human nasopharyngeal specimens to aid in the diagnosis of RSV infection.
Respiratory syncytial virus (RSV) is the most important cause of pneumonia and bronchiolitis in infants and small children. RSV causes a range of respiratory illness, the most common being a cold with profuse rhinorrhea. Of infants infected for the first time, 25-40% develops some lower respiratory tract disease. Between 1 and 2% of infected infants require hospitalization. Because of its high infectivity and because hospital staff as well as patients are susceptible, RSV has emerged as the most frequent cause of nosocomial infections on pediatric wards. RSV belongs to the family Paramyxoviridae and the genus Pneumovirus. It is morphologically similar to other paramyxoviruses with the exception that the diameter of its helical nucleocapsid is smaller, 13 to 14 nm rather than 18 nm. RSV is an antigenically heterogeneous species, with strain differences, which are due primarily to differences in one of the two antigenically active surface components. These differences between strains are probably of little or no practical importance from a diagnostic point of view, since available reagents, including monoclonal antibodies, react equally with all clinical isolates.
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