Savvygen™ GI Bacteria Panel

One Step Real-Time PCR Kits for the for the Detection of Enteric Bacteria- Salmonella, Shigella and Campylobacter

The Savvygen^TM GI Bacteria Panel allows the qualitative detection and differentiation of Salmonella, Campylobacter and Shigella/enteroinvasive Escherichia coli (EIEC) by Real-Time PCR in human stool specimens. The product is intended for use in the diagnosis of Salmonella, Campylobacter and/or Shigella/EIEC infections alongside clinical data of the patient and other laboratory test outcomes.

Gastroenteritis is a major cause of morbidity and mortality, worldwide, both in children 5 years old and in the general population. Campylobacter are gram negative, slender, spirally curved microaerophilic bacteria that live as commensal organisms in the gastrointestinal tract of many domestic and wild birds and mammals. C. jejuni and C. coli are by far the most important human pathogens in the genus and account for more than 95% of all clinical isolates worldwide. The genus Salmonella contains two distinct species, designated Salmonella enterica (divided into six subspecies) and Salmonella bongori. Salmonella species are a leading bacterial cause of acute gastroenteritis. Shigellosis produces inflammatory reactions and ulceration on the intestinal epithelium followed by bloody or mucoid diarrhea. It is caused by enteroinvasive E. coli (EIEC) as well as any species of the genus Shigella, namely, S. dysenteriae, S. flexneri, S. boydii, and S. sonnei. Shigellosis is endemic in many developing countries and also occurs in epidemics causing considerable morbidity and mortality.

Savvygen^TM GI Bacteria Panel test is a ready-to used test, which contains in each well all the necessary reagents for Real-Time PCR assay in a stabilized format. In addition, an internal control allows the detection of a possible reaction inhibition.