Introduction
The SeroPertussis™ product line utilizes purified Bordetella pertussis extract, enriched with PT and FHA, as antigens for detecting specific antibodies for Bordetella pertussis in human serum.
ELISA based serology is the most used approach for laboratory diagnosis with Pertussis Toxin (PT) and filamentous hemagglutinin (FHA) as the preferred antigen combination. The detection of specific IgA and IgM antibodies is indicative of acute infection and is useful for the differential diagnosis of pertussiform syndromes of longer duration. Infants do not regularly produce IgA antibodies before 6 months of age therefore specific IgM antibodies may be used in infants as an indicator of acute infection. IgG antibodies can be used to diagnose active infection when paired sera are available and a rise in antibody level can be demonstrated.
The SeroPertussis™ IgG is semi-quantitative assay using 3 ready to use calibrators P10, P50 and P100 – to draw a calibration curve correlating O.D. readings and arbitrary BU/ml units.
SeroPertussis IgA/IgM is a qualitative assay designed to provide flexibility in detecting IgA and/or IgM antibodies.
Features
- Based on highly purified B. pertussis native antigen enriched with pertussis toxin and FHA
- A set of 3 calibrators (P10, P50 and P75) allows for semiquantitative determination of IgG (as expressed in BU/mL)
- Can detect both B. pertussis and B. parapertussis
- Serum sample
SeroPertussis IgG Cat#A231-01
SeroPertussis IgA/IgM Cat#A233-01
